Computational design of aptamer-based biosensors for the detection of small molecule Toxins
کد مقاله : 1100-PHYCHEM23
نویسندگان
سیده فاطمه سالاری *
دانشگاه صنعتی خواجه نصیرالدین طوسی تهران-دانشکده علوم
چکیده مقاله
In this study, the interaction of OBA3 aptamer with two molecules, ochratoxin A (OTA) and ochratoxin B (OTB) was theoretically explored. To this end, molecular dynamics (MD) simulations on aptamer-OTA and aptamer-OTB complexes were applied to assess their ability in the development of aptamer-based biosensors.
کلیدواژه ها
OBA3 aptamer; ochratoxin A (OTA); ochratoxin B (OTB); molecular dynamics (MD) simulations; biosensor
وضعیت: پذیرفته شده برای ارسال فایل های ارائه پوستر