Computational design of aptamer-based biosensors for the detection of small molecule Toxins |
کد مقاله : 1100-PHYCHEM23 |
نویسندگان |
سیده فاطمه سالاری * دانشگاه صنعتی خواجه نصیرالدین طوسی تهران-دانشکده علوم |
چکیده مقاله |
In this study, the interaction of OBA3 aptamer with two molecules, ochratoxin A (OTA) and ochratoxin B (OTB) was theoretically explored. To this end, molecular dynamics (MD) simulations on aptamer-OTA and aptamer-OTB complexes were applied to assess their ability in the development of aptamer-based biosensors. |
کلیدواژه ها |
OBA3 aptamer; ochratoxin A (OTA); ochratoxin B (OTB); molecular dynamics (MD) simulations; biosensor |
وضعیت: پذیرفته شده برای ارسال فایل های ارائه پوستر |