| Poly (ester-ether-urethane) networks and their interaction with human growth hormone: Conductometry |
| کد مقاله : 1105-PHYCHEM23 |
| نویسندگان |
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معصومه سهرابی *1، پونه سادات پورحسینی1، سمیرا انصاری2 1گروه بیوتکنولوژی، دانشکده علوم زیستی، دانشگاه الزهرا، تهران، ایران 21- CinnaGen Medical Biotechnology Research Center, Alborz University of Medical science, Karaj, Iran. 2-CinnaGen research and production co., Alborz, Iran. |
| چکیده مقاله |
| In this study, the interaction between human growth hormone (hGH) with a di-cationic and a single-chain polymer of poly(ester-ether-urethane) was investigated by conductometry. Thermodynamic parameters of micellization were determined, such as critical micelle concentration (CMC), critical association concentration (CAC), protein saturation point (PSP), and the average degree of ionization (α) of micelles or complexes. The values of CMC for both polymers are low, indicating a good stability of supramolecular structures in aqueous solutions. A comparison of these parameters between both polymers provides a better understanding about their physicochemical behavior in interaction with the protein. |
| کلیدواژه ها |
| Conductivity; Human growth hormone; Interaction; Polyurethane. |
| وضعیت: پذیرفته شده برای ارائه شفاهی |