Synthesis of a modified mesoporous silica for the targeted delivery of Quercetin in Buffer solution (pH=5.3)
کد مقاله : 1120-PHYCHEM23
نویسندگان
مهسا میرزائی باغینی *
شیمی، علوم، شهید باهنر کرمان، کرمان، ایران
چکیده مقاله
In this work mesoporous silica was functionalized with (3-aminopropyl) triethoxysilane (APTES) as the carrier for anti-cancer drug Quercetin. The sample of nano carrier-drug complex was described by BET and an in-vitro drug release test. The release index of the aminopropyl-modified nano carrier exhibited release of Quercetin in applied media. Tests performed in Buffer solution (pH = 5.4) showed the best pharmaceutical availability.
کلیدواژه ها
Mesoporous silica; Drug delivery; APTES; Quercetin; BET
وضعیت: پذیرفته شده برای ارائه شفاهی