Development of molecularly imprinted polymer on ferric oxide nanoparticles modified electrode as electrochemical sensor for detection of the amount of human chorionic gonadotropin (hCG)
کد مقاله : 1154-PHYCHEM23
نویسندگان
سولماز کیا *
دانشگاه محقق اردبیلی- دانشکده فناوری های نوین نمین
چکیده مقاله
A novel molecularly imprinted electrochemical sensor based on Ferric oxide nanoparticles modified glassy carbon electrode was fabricated for detection of human chorionic gonadotropin (hCG). The stable proteins molecularly imprinted polymer films were made by electro-polymerization using aniline as functional monomer and hCG as the template. According to the results, the sensor showed a linear range from 1.0 × 10−10 to 1.0 × 10−7 g/cm3 of hCG (R2=0.9588) under optimal conditions with a detection limit of 0.6 × 10−10 g/cm3. The calibration curve showed a 95.8% correlation of the data. In conclusion, the sensor has sensitivity, high stability and good repeatability.
کلیدواژه ها
Molecularly imprinted electrochemical sensor; human chorionic gonadotropin; Fe3O4 nanoparticles; aniline; square wave voltammetry
وضعیت: پذیرفته شده برای ارائه شفاهی